Home / Open for comment

PROPOSED RULECOMMENTS DUE DECEMBER 9, 2026

Substances Generally Recognized as Safe

Health and Human Services Department / Food and Drug Administration

The Food and Drug Administration (FDA or we) is proposing to require the submission of generally recognized as safe (GRAS) notices for the use of a human or animal food substance purported to be GRAS under the conditions of its intended use under the Federal Food, Drug, and Cosmetic Act (FD&C Act).

Published August 11, 2026Document 2026-16296

How to comment

Comments are due December 9, 2026. Submit through the link above or follow the instructions in the document's ADDRESSES section. Say who you are, how the rule affects you, and what should change, with evidence. Comments are usually public, so leave out anything private.

New to this? Start with our free public-comment guide and example, watch Rulemaking 101 or read How to Comment on Federal Rules.

From the Federal Register as of November 3, 2026. Deadlines can change; the official document governs. Not legal advice.

Know someone following this?

Send them the page so they can check the source and the deadline.